Glutathion and its affects on the immune system

IMMUNE ENHANCING WHEY PRODUCT

is a patented 100% natural food supplement which, taken daily, can support the human immune system. It is not a drug, but a food supplement, and has no known negative side effects.

A powerful antioxidant, replenishes the glutathione levels present in healthy cells and enables them to become active and multiply. This includes the "natural killer" and "T-helper" cells which are essential for the body’s first defense and maintenance of active immune response. However, cells can only multiply if sufficient glutathione is present. Glutathione does not enter cells directly; it must be produced within them from precursors that are present in trace amounts in certain foods, but concentrated in . Significantly, other lesser antioxidants, such as vitamin A, C, and E, only function as long as sufficient glutathione is present. By raising glutathione levels in the cells, combats the damaging effects of free radicals and enhances the immune response.

was developed by a team of scientists who, in 1978, began testing dietary proteins such as casein, soy, wheat, corn, beef, fish egg albumin and algae. Their research, conducted at McGill University (Montreal) under Dr. G. Bounous and Dr. P. Kongshavn, led to the discovery of a milk serum protein isolate that contained unusually high amounts of glutathione precursors which gave support to the immune systems of mammals, including humans. Some 500 liters of fresh, raw bovine milk are required to produce 1 kilogram of .

In experimental research and clinical trails, has demonstrated convincing results in the treatment of major diseases including AIDS and cancer and against high-grade bacterial infections. Further, there is potential for benefit in over fifty diseases which are characterized by low glutathione levels, such as Alzheimer’s and Parkinson’s diseases, arteriosclerosis, hepatitis, and cataracts.

In Canada, France and Japan there have been ongoing clinical trials that demonstrate enhancement of the immune system. has been beneficial in the treatment of AIDS patients, including those with HIV wasting syndrome. Dr. Luc Montagnier, the co-discover of the AIDS virus, drew attention to the promising therapeutic effects of in his opening address at the Tenth International AIDS Conference in 1994. Also, pilot trials with advanced cancer patients in Canada and Japan have confirmed earlier studies which demonstrated significant reduction in the size and incidence of malignant tumors. These promising results are being followed up with further Phase II and III clinical cancer studies.

Glutathione The Essential Antioxidant
"GLUTATHIONE (GSH), A CYSTEINE-CONTAINING TRIPEPTIDE, IS ESSENTIAL FOR THE VIABILITY AND FUNCTION OF VIRTUALLY ALL CELLS."

*"THE DEMONSTRATION HERE THAT LOW BASELINE GSB* LEVELS ARE ASSOCIATED WITH DECREASED SURVIVAL 2-3 YEARS HENCE PROVIDES THE FIRST CLEAR INDICATION THAT GSH DEFICIENCY PLAYS A PIVOTAL ROLE IN DETERMINING HOW QUICKLY THE FINAL STAGES OF HIV DISEASE WILL PROGRESS." *Intracellular glutathione measured as glutathione S-bimane fluorescence. Herzenberg, L.A., DeRosa, S.C. Dubs, J.G., Roederer, M., Anderson, M.T., Ela, S.W., Derensinski, S.C., Herzenberg, L.A., "Glutathione deficiency is Associated with impaired survival in HIV disease." Proc. Natl.Acad. Sci. U.S.A.: Vol. 94, pp.1967-1972, March,1997, Medical Science.

"THIS INVESTIGATION DEMONSTRATES THAT MAINTENANCE OF ADEQUATE PHYSIOLOGICAL LEVES OF GLUTATHIONE IS SUFFICIENT TO PREVENT CATARACT FORMATION." Rathbun, W.B., Holleschau, A.M., Cohen, J.E., Nagasawa, H.T., "Prevention of acetaminophen and naphthalene induced cataract and glutathione loss by CySSME." Invest. Opthalmol. Vis. Sci.: April, 1996.

*"A THREE MONTH ADMINISTRATION OF THE PATENTED WHEY PROTEIN CONCENTRATE *TO PATIENTS WITH HEPATITTIS B RESTORES GSH CONCENTRATIONS IN LYMPHOCYTES TO NORMAL VALUES." * Watanabe, A., Higuchi, K, Yasumura, S., Shimizu, Y., et. Al. "Nutritional modulation of glutathione level and cellular immunity in chronic hepatitis B and C." Abstract. Hepatology: Vol. 24 p.1883,1996.

IS THE NATURAL SOURCE OF GLUTATHIONE PRECURSORS AND LACTOFERRRIN
"LACTOFERRIN AND OTHER CHELATING AGENTS MAY REPRESENT A NEW STRATEGY FOR TREATING METASTATIC RENAL CELL CARCINOMA." Loughlin, K.R., Zhang, H., "The in vitro anti-tumor effect of lactoferrin on human renal cell carcinoma." Abstract. The Journal of Urology: Vol.157, no. 4, Supplement, p.260, April,1997.

"RECENT EPIDEMIOLOGIC EVIDENCE…SUGGEST A ROLE FOR ANTIOXIDANTS IN PROTECTION AGAINST PROSTATE CARCINOGENESIS IN HUMANS." Ripple,M.D., Henry, W.F., Rago, R.P. Wilding, G., "Prooxidant antioxidant shift induced by androgen treatment of human prostate carcinoma cells." Journal of The National Cancer Institute: Vol. 89, No.1,pp. 40-48, January 1,1997.

*"WE REPORT THE IN VITRO SELECTIVE INHIBITORY ACTIVItY OF A HUMANIZED WHEY PROTEIN CONCENTRATE ON GROWTH OF MAMMARY CARCINOMA."

*"IN VITRO STUDIES HAVE CONFIRMED A DIRECT INHIBITORY EFFECT OF WHEY PROTEIN ON HUMAN CANCER CELL REPLICATION." Baruchel,S., Biau, G., "In Vitro selective modulation of cellular glutathione by a humanized native milk protein isolate in normal cells And rat mammary carcinoma model." Anticancer Research: Vol. 16, pp.1095-1100, 1996.

GLUTATHIONE IS THE ACTIVE ANTIOXIDANT IN ISCHEMIC TISSUE
"CARBON-CENTERED FREE RADICALS (C-RADICALS)…CAN BE INVOLVED IN THE DAMAGE UNDER JYPOXIC/ANOXIC CONDITIONS AS WELL AS ISCHEMIA/REPERFUSION INJURY."

"URATE,VITAMIN E AND NON-SH AMINO ACIDS WERE INEFFECTIVE AND ASCORBATE WAS A POOR SCAVENGER OF AAP C-RADICAL. AT VARIENCE, CYSTEINE, AND GLUTATHIONE (O.1-1.0M) WERE EFFECTIVE SCAVANGERS OF AAPC-RADICALS AND, IMPORTANTLY, PROTECTED PLASMA ASCORBATE FROM OXIDATION UNDER BOTH AEROBIC OR ANAEROBIC CONDITIONS. OUR DATA SHOW THAT ASCORBATE IN AEROBIC PLASMA CAN REDUCE VITAMIN E RADICAL AND THE OXIDIZED ASCORBATE MAY BE RECYCLED BY A THIOL*ANTIOXIDANT CYCLE."

"THESE RESULTS SUGGEST THAT ELEVATION IN THE CONCENTRATION OF TOTAL REDUCED THIOLS * IN PLASMA MAY INPROVE ITS ANTIOXIDANT ACTIVITY UNDER HYPOXIC/ANOXIC CONDITIONS." *glutathione Soriani, M., Pietraforte, D., Minetti, M., "Antioxidant potential of anaerobic human plasma: role of serum albumin and thiols as scavengers of carbon radicals." Arch. Biochem. Biopys.: July, 1994.